Cancer Treatment

Radiotherapy

External Radiation (Radiotherapy):
This treatment uses powerful X-rays to penetrate the tumor area, damaging cancer cells during their division, which can shrink or destroy the tumor. To maximize effectiveness, radiation planning is done using a simulation—a cross-sectional scan of the treated area to precisely mark the radiation target. Typically, external radiation therapy is given five days a week for four to six weeks, with each treatment session lasting about 10 minutes.

Internal Radiation (Brachytherapy):
Brachytherapy delivers a higher dose of radiation directly to the tumor, reducing radiation exposure to surrounding healthy tissues such as the intestines and bladder. This treatment complements external radiation and is crucial for achieving a cure.

While the external radiation plan is consistent throughout the treatment days, brachytherapy is planned on the same day of treatment based on a simulation performed at the time, allowing for much greater precision and significantly increased treatment effectiveness. 

Brachytherapy typically begins two to three weeks after starting external radiation. The number of treatments ranges from four to five, given once or twice a week. It is essential to maintain this schedule without delays to achieve the most effective results.

In most cases of cervical cancer, brachytherapy is therapeutic. 

In most cases of endometrial cancer, brachytherapy serves as preventive radiation, providing a boost to prevent cancer recurrence.

General Anesthesia During Applicator Placement:
General anesthesia is administered only during the placement of the applicator. Once the applicator is in place, you are moved to the recovery room and awakened from anesthesia (general anesthesia requires the presence of an anesthesiologist in an operating room). Upon waking you may begin to feel discomfort, and the medical team typically provides pain relief to help manage this sensation.

Spinal Anesthesia:
The main difference between the two types of anesthesia is that spinal anesthesia lasts about 3 hours (covering the entire treatment), while general anesthesia lasts only 20 minutes (during applicator placement). After 20 minutes, pain medications are provided as needed based on your pain level.

Although spinal anesthesia might seem intimidating, the injection takes only about 10 seconds, after which you typically feel very little for an extended period.

LDR (Low-Dose Rate) – Radiation is delivered at a low dose over several days.

HDR (High-Dose Rate) – Radiation is stronger, with each treatment lasting a very short time, typically only 5 to 20 minutes.

In Israel, HDR is commonly used.

In brachytherapy, radiation applicators are used to deliver radiation precisely to the tumor area. There are several types of applicators, and the physician selects the most appropriate one based on the treatment goal, tumor location, and medical condition.

Types of Applicators:

PLV (Partial-Length Vaginal) Brachytherapy

FLV (Full-Length Vaginal) Brachytherapy

Depending on the applicator type, the procedure may be performed with or without local or general anesthesia to prevent pain.

Before Your First Brachytherapy Session

Before your first brachytherapy treatment, you will need to meet with an anesthesiologist. This appointment should be scheduled after you have completed a urine test, blood tests, and an ECG. Following your meeting with the anesthesiologist, you will undergo the remaining necessary tests with the guidance and support of the medical team at your treatment center.


Each time before a brachytherapy session, 1-2 days in advance, you will need to have blood tests (similar to those required before chemotherapy). It is recommended to send the test results to the secretary or nurse at the clinic where you are being treated and confirm that the results allow you to proceed with the brachytherapy on the scheduled date.

On Treatment Day

Though the procedure may vary slightly between clinics, we will be discussing international guidelines here. In most clinics, brachytherapy is performed in the afternoon, which helps facilitate a smooth treatment process since most external radiation treatments are given in the morning. You will receive specific instructions from your clinic about fasting times for food and drink.


Preparation at Home:

Fasting:

  • It is crucial to have a full breakfast before starting your fast, and to take your regular medications with this meal.
  • Refrain from eating in the 6 hours leading up to the treatment.
  • Refrain from drinkning in the hour leading up to  the treatment.
  • This fasting is essential because you will receive sedation or anesthesia, and your stomach must be empty to prevent regurgitation during the procedure, which you undergo lying down.

Bowel Preparation:
About 3 hours before arriving at the clinic, perform a small enema (Microlax) to clean the lower bowel. This is usually performed twice. Bowel preparation is essential as it helps move the bowel away from the radiation area, thereby reducing side effects.

Treatment Process

The entire treatment, from admission to discharge, usually takes about 3-4 hours. It is important to arrive at the clinic on time to help reduce the duration of the session and wait times for yourself and for other patients receiving brachytherapy that day.


You will stay in a recovery room during the treatment, while applicator placement and radiation are performed in a brachytherapy room (a separate operating room equipped with everything needed for the procedure).


On treatment day you will:

  • Arrive at the clinic and be admitted by a nurse who will accompany you throughout the treatment.
  • Upon arrival, you will receive a bed and change of clothes, have your vital signs checked (blood pressure, pulse, and some general questions), and sign a consent form.
  • After changing clothes, you will meet with the anesthesiologist, and have an IV inserted.
  • When it is your turn, the staff will escort and guide you to the brachytherapy room.
  • In the brachytherapy room, if necessary, local (spinal) or general anesthesia will be administered.
  • After receiving anesthesia, you will lie on a bed similar to a gynecological exam table, with a screen separating you from the area being treated.
  • The doctor will perform a gynecological exam and insert a urinary catheter so you won’t need to get up to urinate. The doctor will then place the applicator in the tumor area. This procedure takes about 20 minutes and is not painful.
  • After placing the applicator, the staff will carefully transfer you back to your bed and take you for a simulation (using MRI or CT) to ensure the applicator is correctly positioned at the tumor site. After the simulation, you will be returned to the recovery room.
  • While in the recovery room, the staff will plan the radiation for that day based on the simulation results. This planning takes about 40 minutes, during which you can rest. Because the applicators are in place, you must not move your legs or head to avoid displacing them.
  • Once the radiation plan is complete, you will be taken back to the brachytherapy room, where the applicator will be connected to the radiation source. The radiation session lasts between 5 to 20 minutes, depending on the equipment used (duration is not related to tumor size). After the radiation, the applicators will be removed, and you will be returned to the recovery room.
  • After some time, once the anesthesia has fully worn off, you will be discharged home.

After the treatment:

You may experience spotting, bleeding, or vaginal discharge after the applicator is removed. It is recommended to bring an absorbent pad.
You might have cramps similar to menstrual pain for up to 24 hours after the procedure. You can use pain relievers to alleviate the cramps.
You may feel a burning sensation when urinating for up to 24 hours. It is advisable to drink 8-10 glasses of water a day.
Some may experience diarrhea.
It is recommended to avoid sexual intercourse during treatment due to possible vaginal sensitivity and irritation.
You are not radioactive in any way after the procedure, and can safely be around family and friends.
You can eat normally and continue your regular activities throughout the treatment.
When to Seek Emergency Care
You should go to the emergency room if:
You develop a fever above 37.8°C (100°F) within 48 hours after the treatment.
You experience pain that does not subside with pain relievers.
You have heavy bleeding, such as filling a night pad within two hours.
You notice a burning sensation or blood in your urine lasting more than 24 hours after the procedure.
You have not had a bowel movement for 3-4 days after the procedure.

 

When to Seek Emergency Care

You should go to the emergency room if:

  • You develop a fever above 37.8°C (100°F) within 48 hours after the treatment.
  • You experience pain that does not subside with pain relievers.
  • You have heavy bleeding, such as filling a night pad within two hours.
  • You notice a burning sensation or blood in your urine lasting more than 24 hours after the procedure.
  • You have not had a bowel movement for 3-4 days after the procedure.

 

 

We make every effort to provide evidence-based and reliable health information. We invest significant time and resources to ensure the information on our website is as accurate and up-to-date as possible, supported by scientific sources and aligned with current professional knowledge in relevant fields. However, the information in this website does not constitute medical advice or recommendations. We encourage anyone seeking personalized advice or recommendations on medical matters to consult directly with a licensed physician or a certified healthcare professional in the relevant field.

1/11/24

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